Prostate Cancer: A Personalized Approach to Screening
PSA testing requires informed discussion.
Dr. Anne-Sophie Lefèvre
Oncologist
PSA testing detects cancers earlier but also indolent ones. Shared decision-making between ages 50-70 (45 for high-risk men) balances benefits and harms.
Diagnostic pathway
Elevated PSA leads to MRI-targeted biopsy when needed. Genomic tests help estimate aggressiveness.
Active surveillance
Low-risk localized cancers can often be monitored rather than treated, sparing patients side effects without compromising survival.
Treatment
Surgery, radiotherapy, androgen-deprivation therapy and newer hormonal agents (abiraterone, enzalutamide) tailor to disease stage and patient priorities.
A single elevated PSA does not mean cancer: infection and benign enlargement are common causes.
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