Conditions

Thyroid: Hypothyroidism and Hyperthyroidism Explained

This small gland that regulates everything.

Dr. Marc Dufresne

Endocrinologist

7 min read
Medical illustration of Thyroid: Hypothyroidism and Hyperthyroidism Explained

In simple terms

Thyroid dysfunctions affect 10% of the population, with a female predominance. Symptoms, diagnosis, and treatments.

What you need to remember

  • Hyperthyroidism (overactive thyroid)Weight loss despite preserved appetite

The thyroid is a butterfly-shaped gland located at the base of the neck. It produces T3 and T4 hormones, which regulate the metabolism of almost all body cells.

Hypothyroidism (underactive thyroid)

Symptoms

  • Persistent fatigue
  • Weight gain despite normal eating
  • Excessive sensitivity to cold
  • Constipation
  • Dry skin, brittle hair
  • Intellectual slowdown, memory problems
  • Depression

Most frequent cause

Hashimoto's thyroiditis: an autoimmune disease where the immune system attacks the thyroid.

Treatment

Levothyroxine (synthetic thyroid hormone) for life, with dose adjustment according to TSH.

Hyperthyroidism (overactive thyroid)

Symptoms

  • Weight loss despite preserved appetite
  • Palpitations, tachycardia
  • Nervousness, irritability, tremors
  • Heat intolerance, excessive sweating
  • Diarrhea
  • Insomnia

Most frequent cause

Graves' disease: an autoimmune disease stimulating the thyroid.

Treatments

  • Antithyroid drugs (carbimazole, propylthiouracil)
  • Radioactive iodine
  • Surgery (thyroidectomy)

When to check your thyroid?

  • Persistent unexplained fatigue
  • Weight variation without lifestyle change
  • Mood disorders resistant to treatment
  • Family history of thyroid disease
  • Postpartum (postpartum thyroiditis)

A simple TSH test is enough to screen for thyroid dysfunction. It is an inexpensive and very informative routine examination.

The words explained

Medical terms used above, in everyday language.

Symptom
A sign you can feel or see that something is wrong, like pain, tiredness or a rash.
Hormone
A chemical messenger made by your body that tells organs what to do.
Metabolism
How your body turns food into energy and builds or repairs itself.
Immune system
Your body's defence team: cells that fight germs and repair damage.

When should you see a doctor?

  • Your symptoms last more than a few weeks or keep coming back.
  • They get worse quickly, or stop you doing everyday things.
  • You notice sudden pain, breathing trouble, fainting or bleeding — seek urgent care.
  • You already take medication and want to change anything about it.

This article explains general health information. It does not replace advice from your own doctor.

Frequently asked questions

What is Thyroid: Hypothyroidism and Hyperthyroidism Explained?
Thyroid dysfunctions affect 10% of the population, with a female predominance. Symptoms, diagnosis, and treatments.
What are the main symptoms or signs of Thyroid: Hypothyroidism and Hyperthyroidism Explained?
Common signs vary from person to person. The article above lists the symptoms to watch for, how they progress, and when they need medical attention.
When should you see a doctor for Thyroid: Hypothyroidism and Hyperthyroidism Explained?
See a doctor if symptoms last more than a few weeks, get worse quickly, stop you doing everyday things, or if you notice sudden pain, breathing trouble, fainting or bleeding.