Hepatitis C: cure now possible
Direct-acting antivirals: >95% cure rate
Dr. Inès Bertin
Hepatologist
A long silent virus
HCV often infects the liver asymptomatically, progressing to cirrhosis or liver cancer after 20-30 years. Transmission is mainly blood-borne (IV drug use, old transfusions, poorly sterilized equipment).
Expanded screening
health authorities recommends universal screening at least once in a lifetime for adults. Simple serological test (anti-HCV), confirmed by PCR.
Revolutionary treatment
Direct-acting antivirals (sofosbuvir/velpatasvir, glecaprevir/pibrentasvir) in 8 to 12 weeks cure more than 95% of patients, all genotypes combined, with very few side effects.
After cure
Liver monitoring if advanced fibrosis (persistent risk of hepatocellular carcinoma). No immunity: possible reinfection in case of new exposure.
Also read
Infectious Diseases
Hepatitis B: A Manageable Chronic Infection
Around 250 million people live with chronic hepatitis B. Modern antivirals suppress the virus indefinitely.
Infectious Diseases
Hepatitis C: A Curable Disease Today
Hepatitis C used to mean lifelong chronic liver disease. Modern 8-12 week regimens cure nearly all infections.
Infectious Diseases
Recurrent Urinary Tract Infections in Women
Half of women experience at least one UTI; 25% develop recurrences. Several non-antibiotic measures reduce recurrence.