Bones, Joints & Muscles

Fibromyalgia: A Real Disease of Pain Processing

Multimodal treatment outperforms any single therapy.

Dr. Inès Da Costa

Rheumatologist

6 min read
Medical illustration of Fibromyalgia: A Real Disease of Pain Processing

In simple terms

Fibromyalgia is recognised as a central pain syndrome, not 'in the head'. Comprehensive care brings real relief.

What you need to remember

  • TreatmentEducation and pacing strategies
  • What does NOT helpStrong opioids worsen long-term outcomes; chronic NSAIDs offer limited benefit.

Widespread pain >3 months, severe fatigue, non-restorative sleep, cognitive 'fog', and often coexisting irritable bowel and migraines.

Diagnosis

Clinical; no specific test. Rule out hypothyroidism, vitamin D deficiency, inflammatory arthritis.

Treatment

  • Education and pacing strategies
  • Graded aerobic exercise (the most consistent evidence)
  • Sleep hygiene
  • Cognitive behavioural therapy
  • Selected medications: duloxetine, pregabalin, amitriptyline

What does NOT help

Strong opioids worsen long-term outcomes; chronic NSAIDs offer limited benefit.

Pacing, not pushing through, prevents the boom-and-bust cycle typical of fibromyalgia.

The words explained

Medical terms used above, in everyday language.

Chronic
A problem that lasts a long time, usually more than three months, and often comes back.
Inflammation
The body's reaction to injury or irritation: redness, swelling, heat or pain.
Diagnosis
The moment a doctor identifies which illness is causing your symptoms.
Prevention
Steps taken before a problem starts, to make it less likely.
Cognitive
Related to thinking: memory, attention, learning and decision-making.

When should you see a doctor?

  • Your symptoms last more than a few weeks or keep coming back.
  • They get worse quickly, or stop you doing everyday things.
  • You notice sudden pain, breathing trouble, fainting or bleeding — seek urgent care.
  • You already take medication and want to change anything about it.

This article explains general health information. It does not replace advice from your own doctor.

Frequently asked questions

What is Fibromyalgia: A Real Disease of Pain Processing?
Fibromyalgia is recognised as a central pain syndrome, not 'in the head'. Comprehensive care brings real relief.
What are the main symptoms or signs of Fibromyalgia: A Real Disease of Pain Processing?
Common signs vary from person to person. The article above lists the symptoms to watch for, how they progress, and when they need medical attention.
When should you see a doctor for Fibromyalgia: A Real Disease of Pain Processing?
See a doctor if symptoms last more than a few weeks, get worse quickly, stop you doing everyday things, or if you notice sudden pain, breathing trouble, fainting or bleeding.